It also has the benefit of making any genetically female slaves fear you less right away. I never play as a man again and relish the challenge. You can use this to your advantage with a religious and paternalistic society. But first you have to get established before you can fully take advantage of that.
In the beginning of the game, unless you're handicapping yourself, you want to make a bunch of slaves who will become your leaders. You can cut the costs down to just 2000 each by making them all very ugly, flat chested and assed, as well as highly hateful of you and afraid. Don't forget to make them all geniuses. Give them all the attributes they need to be in leadership positions. Even if you're doing a challenge run, at the very least make a head girl who has a dick and a pussy, is over 40 and is an expert in everything but combat. And a genius. You'll later train your head girl and assign her to whore and entertain the public, letting her become a master whore, master entertainer and sex master. Later, this turns her into a money factory.
In the early game, your reputation will be low anyways, so embrace it. You can open up a big arcade and throw all the junk slaves in there. -Don't- get the aphrodisiac upgrades in the arcade.DO make it milk slaves. You're looking at potentially 700 for slaves with dicks and balls and 500 for genetic females that lactate. Per slave. DON'T give slaves contraceptives. This is an added expense and slaves being pregnant doesn't really matter for our strategy.
In any events you get, always pick the one that provides money or benefit to yourself, ignoring any kind of social consequence. You don't care what other people think, you just want to make money. Only do things that raise prosperity or get you paid. Buy the security drone archology upgrade and then don't bother with more until your archology reaches enough prosperity that it needs to upgrade to increase your rents. You can spend the arcade cash on expanding your operations.
A nice early game boost is having started with a valuable slave, left by the previous owner. Sell her when the market is high. The money will come in handy.
Once you get a lot of money, you start by buying all of the slaves you can afford. Since the only place you can access for now is the main kidnapped slave market, you never want to spend more than 2000 on one, unless you're spending 4000 for a high intelligence or natural beauty virgin.You can collect virgins as they'll be worth a lot of money to you as a side project later. Be sure to pick up all the shemales you can, they're the most valuable slaves in the game. At this point I typically buy 20 slaves, depending on capital.
When you're investing in a facility that has workers in it, remember that you'll need at least 15000. You'll spend 5000 on the upgrade and at least 2000 for 5 slaves. Take any virgins you acquired and start abusing them. You want to terrify them to the point where you can put them into the servant's quarter. They'll reduce your upkeep, making you more money, but also it's a good place to keep them organized. Any other slaves get filtered through to the other facilities.
The cock milking facility provides as much money as the arcade does, but at higher upkeep and requires a skilled slave to get the most money out of it. You can place any shemales you buy in here, along with giving them lactation implants. It's time consuming, but you'll make a lot of money.
The milking facility makes extra money from slave pregnancies, so throw all of your ugly or older genetic females in here, after they have lactation implants. The money here isn't much to write home about, but all profit is good profit.
The brothel makes money based on how attractive and skilled the slaves are. The other facilities will provide more money until you get more of these kinds of slaves. Still, money is money. Once again, don't buy the aphrodisiac upgrade.
The developer didn't factor in people having lots of lots of slaves in here(50+), so what it does is basically doubles your upkeep. A typical slave only costs 100 a week for the bed she sleeps on. The drugs add another 100, cut by half with a later pharmacy upgrade. Overnight, you'd go from spending 5000 for your 50 slaves to 10000. These drug upgrades are never worth it. The amount they add simply isn't enough.
The other facilities such as the club, spa and master suite can be done at your leisure. They're not as useful until you're richer.
The prison can be used to quickly break slaves so they can be tossed into the brothel or head girl suite, allowing my favorite trick of the game. It's as follows.
You want to take your head girl and give her a suite, as well as putting an attractive and intelligent slave in there. This slave will be personally trained and molded by the head girl. Next, you buy two more virgins and terrorize them, then toss them into the servant's quarters. Then take two of your other stored virgins out. You place every slave you have other than your recruiter, head girl and body guard in some sort of facility.
From now on, your head girl will train, discipline, nurse or break the quirks of TWO slaves per week. Along with training the one in her suite. So in 15 weeks, assuming she trains every week, you'll have two virgins who are masters at anal, vaginal, oral, prostitution and entertainment. If they're really pretty and smart and the market is up at the moment, you're looking at being able to sell them for many thousands. Once you do so, you buy 20 more slaves, stock the virgins in the servant's quarter, and then fill out the rest of your facilities.
One thing to note is that the household liquidator is a very good deal. The game starts to lag after you get over 100 slaves and it saves time to spend 6000 to buy 2 slaves who are related to each other rather than get 3 that you'd have to click through multiple menus to buy. I almost never buy slaves from the regular market after unlocking the liquidator and being at past 100 slaves.
Also of note, the auctions are also a really good deal. You can get fantastically skilled and prestigious slaves from there. And also, some of the premade slaves you can buy direct from other slave owners are fantastically overpowered, but they lack prestige and aren't often as good a deal. Some of them are worth it though.
FINALLY! The last big money making opportunity comes from having a master gladiator, a young, strong, tall, sadistic, trained killer murder a slave every week in the fight pits. At the very least, you'll get 4000, but there seems to be a max of 20000. So worst case scenario, you double your money. Best case, you make a 'killing'. Unfortunately, the game doesn't have a place to reliably, cheaply buy trained killers. Or rather it does, but you'll need to have a high reputation already to access the premade slaves and buy one of the killers from there. Who you'd then buy again every week after she gets killed. You can affectionately nickname her "Kenny" and give her an orange parka.
But some of you might not feel comfortable doing the above, so feel free to just make the fights non lethal and get two trained fighters who duke it out every week. Maybe you can keep them in the spa when they aren't fighting?
The corporation is really cool. Buy low on medicine and training and slave capture stuff. Always invest more money in stocks. Eventually this will pay out a ton of cash which can cover your upkeep costs. Then your rents will just be gravy.
Eventually, you might start caring about your reputation, so you can later on start tossing slaves into the master suite and club. Adopting a degrading society will remove the reputation penalties from having an arcade. If you care about that.
As far as society options go, the only worthwhile ones are the roman and Egyptian ones, the paternal, degrading, the religious and the milking. Some of the other ones should really be fused or simply -do- more things to actually be worth it. All of the above stand head and shoulders over the others available and provide nice perks.
I highly suggest milking. Two of your facilities are boosted by it and it practically doubles your income. Get this as soon as you possibly can.
Hope this helps. You'll make millions.