Synthetic transformations. Gynoid, etc. Used to have fantasies about the sex bots transforming you into one.
More forced/involuntary transformations. I know some people aren't fans but then I can argue there are plenty of items in game to undo them, but there aren't a ton in there for those that enjoy them.
More Sera domme stuff. Seriously.. my favorite part of the game.
More S&M in general. I like it. I am not apologetic for that. Maybe some shipboard scenes with your companions going both ways, I always set Bess up as my domme. Would be neat if as part of the sleep mechanic she woke you up with scenes. Maybe even punish you if you don't speak to her often enough.
More to do with ships. More random space missions.
I'd like to see some revenge against your cousin. Its not enough to keep beating him/her to the probes. I wanna see them suffer some. TFs, etc.
Less bad endings. Okay, I know I am not gonna get that one.. but I hate them personally.