All the previous have a more or less pleasant resolution: We can simply don't use the Treatment, and happily interact with the New Texans anyway (specially Busky <3), or avoid the planet entirely, deal with Badger in many ways (on my case, doing the right thing and sending her to jail), and as you pointed, solving the conflict in Myrellion (waiting patiently for a gold-based resolution around late '17).
The bigotry of the mentioned woman is quite more, troubling, that the given examples, since I see Sera as a stressed girl that gets too riled on superficial matters, but can care for someone no matter how they look given the time, and I don't view XIX century colonialism as something entirely negative, at least, not enough to antagonize Darnock.