If you help her on her quest, thus enabling her self-destruction, Saendra will gladly sail out into the stars on a spaceship held together by duct tape and hope.
Of course, it's worth noting that a man dies if you don't help to enable her self-destruction, unless you just leave her hanging after SQ1. Following Saendra may be necessary not to protect her, but to protect the other people that she's putting in harm's way.