To throw in my Two Cents, I personally find the Treatment to be one of the most polarizing transformatives. On the one hand, I love the physical effects and perks. On the other, I hate the mental changes. And this feeds into the atmosphere of New Texas itself. I think it was said best earlier in the thread, very Crapsaccharine. Though, that said, I personally like all the NPC's, and the planet itself is pretty laid back. Plus, varmints. Now my Mercenary can have a companion!
Plus, why would there be a nuke on New Texas? Like, unless Savin ever finishes the Under Big T Manor dungeon, and you trigger the old colony ship's engines, I don't see how you would wipe out the ranch...