I don't tend to opt for 100% human, but I do as a rule prefer to stick with the initial hybrid race.
The exception is if my build requires a particular anatomy or if it enables a particular kink the character is aiming for.
Case in point, my Melee Techie started as a half-kaithrit, but she's become something of a chimera because I needed wings for her to clap airborne enemies with her Shock Gear, and no the Jetpack isn't an option either since I want to run the Steeletech Laser Drone+Combat Tail wombocombo. So I swallowed enough Dracoguard Pills to until I had flight-worthy wings,
I also wanted Red Myr venom not to optimize my build but because that shit is just hot to me, especially from the dominant's perspective. >///>
The OC she draws inspiration from basically functions like a Dzaan Alpha (because she in turn is at least partially inspired by the Dzaan.) so... since there's no TF for Dzaan I'm opting for the saliva instead lol.