In my opinion, Galomax's biggest downside is the fact that you lose your human appearance. It's super useful, but even if governments and private corporations weren't scrambling to get a literal piece of you for testing (and, let's be real here, your genes could very well harbor the secret for immortality, SOMEONE is going to be sending hitmen after you and I honestly don't even blame them), you'd be completely socially isolated if you ever revealed your actual body. There are definitely ways around this, like stuffing yourself into a specially-made skin tight suit or something, but it would still be really stressful to keep track of all day, every day. On paper, Galomax effectively gives you superpowers and no other mod in the game really comes close to that, aside from maybe the Treatment, which has the POTENTIAL (not guaranteed) to give you incredible height and near-inhuman levels of strength, but the cost for it is a lot higher than most other mods and there really aren't that many chances to use those specific powers in most people's day to day lives.
Rather ironically, considering everything I just said about standing out, however, I feel like I'd take Dove Balm as my ideal irl TF. Mostly because I feel like angel wings would be a lot more socially acceptable than being a full-on goo creature, and the ability to fly is incredibly useful from a fun and utility perspective. I might get some odd looks every now and then depending on how tightly I could fold them against my back to try to keep them hidden, but I feel like it would be a lot more of a positive than a negative as far as social perception goes once the fuss died down.
