Obligatory mention of
https://tfgames.site/?module=search&transformation=4 with the standard disclaimer that many of those games are incomplete and sometimes awful. Some that I think go that large (but I could be mistaken: )
- pixiespawn festival (roguelike, similar to trapquest)
- No Haven / Whorelock's Revenge (one you play as a slaver, the other as a slave)
- Queen Of The Seas (Haven't played it, but the blurb shows huge boobs)
- The Company (Boobs can get pretty large, but also the story line gets so dark I can't recommend it any more)
- XXXivilization (strategy game, I think you can keep growing your boobs)
- The Ooze Wizard Appretince
- Parasite Infection (the author has a habit of breaking things every so often, but worth a look)
- Boobjitsu matriach
I'm sure there are others (especially some of older, better games) but I skimmed through the last year's worth of entries and those are the ones that stood out.