Yes.To grossly oversimplify: it's more likely to be buggy/crash compared to a stable version, generally due to new additions still being in testing.
To be honest, I think I got one annoying bugs; there is thing is now call demonic energy which you can get from being soulless and having soul eater which you get being demon and quests.
There is infinite grow potential options having demonic energy though consuming lethice items which make also it possible upgrade element dao mastery and to boost comparable or surpassing to might magic at 16000%. It is kind of easy to keep the energy at set value with cheat engine and the limit bsically your mental limit at this point.
The main issue is while making update to stats, it does not really show on the save normally. I had to used to use new save for saving and reloading sometime twice.
There is an option for dark ascension, when you have those perks; there is seems to be unstated to element dao boost from it, my character starts with 30% percent resistances in all elemental dao and without dark ascension the resistances start at 0%; it can do some insane changes like having boost an element and weakness to its weakening element and vice versa still can keep the resistances to 100%.
It seems magic resistance is much lower in a dark ascension save, I manage to get 80% magic and physical damage resistances with less effort normally; in this new save with dark ascension, I have to put more effort in getting more monster mutations since it was mostly at 50% while the physical damage resistance was 80%.
Another issue is there 4 human bloodlines, at point that you get them, it seems like when you have the supremacy perks and human mutations, you human racial score does not really decrease from other mutations. Mine is still above 100 despite having multiple mutation from races and those mutation scores does not show as negative for human score.
Edit: from discord about the primarch human bloodline, "primarch one allow to have as amny non human IM's you want without affecting human score". Honestly, I wish it was stated in the game description.
There is the new UI for racial scores where I cannot transform as kitsune or human in it while the old UI, I still can; the same issue that I mentioned about the racialscore transformation still exist though:
New normal state:

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How do I raise her affection level?