Starbound of course, too many hours spent playing Terraria to not look forward to another exploration-builder.
Dragon: the Game. This one's a weird one, being a sucker for dragons and having played Panzar Dragoon, I was looking forward to an open world game where you can play as a dragon, customize yourself into any kind of dragon you want to be, and go terrorize or befriend humans. The development to this game is bit slow though, so I can only hope it doesn't get scrapped.
Warhammer 40k - Eternal Crusade. A game in development that is a sort of mix between Planetside and Space Marine. I'm hoping it gets off the ground eventually, so that I might slay some Mon'keigh scum.