I assume you're a Smuggler.
She has relatively weak Reflexes. If you've maxed Reflexes, Mag Binders should always work.
Grenade Launcher (Flash Grenades) are likely to Blind if you have good Aim (and have gone through her Armor).
She's weak to all Lust damage types.
There's an optional fight to the South. If you beat it, Johana will help you fight Hureya.
What Perks did you take and what are your Stats?
Are you getting chain-grappled? There was a
bug report earlier. Feel free to post to it.