On the subject of the spider quest, I think there may be a bug, for some reason if I ever loaded after accepting the quest but before completing the Fei An Strozo diplomacy part, Fei An Strozo just wouldn't appear any more, the spider web would also appear in front of the taxi before I got three of the diplo'd 3 quadommes it just couldn't be interacted with, even if I started a new game.
(Edit: Okay, it seems the issue is with the auto save system not the save files themselves, I can get saves to work by loading the saves after deleting the auto save, but that is a bug right? I don't think the game should punish players for failing to complete a mission in a single run, "on an entirely different play through".)
(Disclaimer: I am using save editor but I've never had this kind of thing happen before, I didn't even realize there was a type of autosave prior to this, atleast that's what I assume that file was it just had a bunch of numbers for a file name, and it was found in folder username/appdata/roaming/com.taintedspace.tits/#airversion)
(Edit2: it just occured to me that there may be a bugs section, I'll go look at the rules and post this over there, sorry about this, oh and the game version is TiTS 0.7.143)