Lose to Arona enough times during Right of Conquest and you'll be locked in to her taking a dominant role towards the Champion, which affects a couple of things during and post-quest right now (for example, wander into the lodge and you won't get the option to simply refuse the attentions of the patrons, because they know you're Arona's bitch) and will no doubt become a much bigger deal once her companion expansion gets implemented.
There's also Evelyn who's basically there for players who like the idea of getting into a consensual domme/sub relationship.