Also a good reason to have at least one weapon in your inventory that deals different typed damage than what you run ie: non-energy weapon if you're a techie, energy weapon if you're a merc.Insanity is doing the same thing repeatedly and expecting different results. Pretty sure drilling that home was the entire purpose of the tutorial fight against Celise. Phys/Gun/Lust; pick one. If it doesn't work, pick a different one.
Don't use an Energy weapon -- she's mirrored, making her nigh immune.