As well as Marblak's suggestions I would throw in The Company (which gets very dark) and Parasite Infection (icky.) There's also a game where you run a spa that has a bimbo-ification device and you make choices about how much to use it on people, but I can't remember what it's called.
There's also a game where you run a spa that has a bimbo-ification device and you make choices about how much to use it on people, but I can't remember what it's called.